471232

Dibutylamine

≥99.5%

• Synonym(s): N,N-Di-n-butylamine, N-Butyl-1-butanamine, n-Dibutylamine, Di-n-butylamine
• Linear Formula: (CH₃CH₂CH₂CH₂)₂NH
• CAS Number: 111-92-2
• Molecular Weight: 129.24
• Beilstein: 506001
• EC Number: 203-921-8
• MDL number: MFCD00009429
• UNSPSC Code: 12352100
• PubChem Substance ID: 24870706
• NACRES: NA.22

Properties

• vapor density: 4.46 (vs air)
• vapor pressure: 1.9 mmHg ( 20 °C)
• Assay: ≥99.5%
• form: liquid
• autoignition temp.: 594 °F
• expl. lim.: 10 %
• refractive index: n20/D 1.417 (lit.)
• pH: 11.1 (20 °C, 1 g/L)
• bp: 159 °C (lit.)
• mp: −62 °C (lit.)
• solubility: water: soluble 3.8 g/L at 20 °C
• density: 0.767 g/mL at 25 °C (lit.)
• functional group: amine
• SMILES string: CCCCNCCCC
• InChI: 1S/C8H19N/c1-3-5-7-9-8-6-4-2/h9H,3-8H2,1-2H3
• InChI key: JQVDAXLFBXTEQA-UHFFFAOYSA-N

Description

General description

Dibutylamine is a highly reactive catalyst, commonly used as a reagent in the derivatization of isocyanates.

Application

Dibutylamine can be used as a reactant to synthesize:,·      

• N, N

• -Dibutyl-4-methylaniline by Pd-catalyzed Buchwald-Hartwig amination reaction with aryl chlorides and bromides.     
• N,N-Dibutylacetamide by acetylation reaction with isopropenyl acetate.

It can also be used as:      

• A strong hindered base in the different elimination reactions.
• An organocatalyst to synthesize annulated pyrano[2,3-d]pyrimidine derivatives via multicomponent condensation reaction of aromatic aldehydes, malononitrile, and barbituric acid.

Safety Information

• Pictograms: GHS02,GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H226,H302,H311,H314,H330
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 104.9 °F - closed cup
• Flash Point(C): 40.5 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves