V3501

Vitamin K₁

viscous liquid

• Synonym(s): 2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, Vitamin K₁₍₂₀₎
• Empirical Formula (Hill Notation): C₃₁H₄₆O₂
• CAS Number: 84-80-0
• Molecular Weight: 450.70
• Beilstein: 2568816
• EC Number: 201-564-2
• MDL number: MFCD00214063
• UNSPSC Code: 12352205
• eCl@ss: 34058015
• PubChem Substance ID: 24900741
• NACRES: NA.28

Properties

• biological source: synthetic (organic; inorganic)
• form: viscous liquid
• color: yellow to orange
• refractive index: n20/D 1.527 (lit.)
• mp: −20 °C (lit.)
• density: 0.984 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O
• InChI: 1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1
• InChI key: MBWXNTAXLNYFJB-NKFFZRIASA-N

Description

General description

Vitamin K1/Phylloquinone is a prenylated naphthoquinone. It is produced by plants, green algae and some species of cyanobacteria.

Application

Vitamin K1 has been used in the preparation of culture media.

Biochem/physiol Actions

Vitamin K1 (Phylloquinone) is a lipid soluble polycyclic aromatic ketone used as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X; anticoagulant factors protein C and S and as a cell signaling factor. Vitamin K1 is essential for blood coagulation, bone and vascular metabolism. Phylloquinone from green leafy vegetables and vegetable oil is the most important dietary source of vitamin K for humans.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves