SRE0016

MATP+

substrate for analysis of acetylcholinesterase (AChE) activity

• Synonym(s): 1,1-dimethyl-4-acetylthiomethylpiperidinium iodide, acetylcholinesterase substrate, MATP+
• Empirical Formula (Hill Notation): C₁₀H₂₀INOS
• Molecular Weight: 329.24
• UNSPSC Code: 12352204
• PubChem Substance ID: 329826113
• NACRES: NA.83

Properties

• product name: MATP+,
• storage temp.: 2-8°C
• Quality Level: 200
• SMILES string: CC(SCC1CC[N+](C)(C)CC1)=O.[I-]
• InChI: 1S/C10H20NOS.HI/c1-9(12)13-8-10-4-6-11(2,3)7-5-10;/h10H,4-8H2,1-3H3;1H/q+1;/p-1
• InChI key: WLNVGCIMLLIQAL-UHFFFAOYSA-M

Description

General description

1,1-Dimethyl-4-acetylthiomethylpiperidinium iodide (MATP+) is a substrate for analysis of acetylcholinesterase (AChE) activity.  MATP+ is highly selective for specific detection of AChE activity, and thus is advantageous over other AChE substrates like acetylcholine, which can react with multiple enzymes like AChE and also butylcholinesterase (BChE).  Thus with MATP+ in the AChE assay, there is no need to include BChE inhibitors in the protocol.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable