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Key Documents

SAB2501175

Sigma-Aldrich

Anti-MARCH10 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-FLJ35757, Anti-MARCH-X, Anti-RNF190, membrane-associated ring finger (C3HC4) 10

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, bovine, rat

technique(s)

indirect ELISA: suitable
western blot: suitable

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MARCH10(162333)

General description

Membrane-associated RING-CH-type finger 10 (MARCH 10) protein is a non-canonical member of the MARCH family. It is expressed in the cytosol, developing spermatids and elongated spermatids. The MARCH10 gene is mapped on the human chromosome at 17q23.2.

Immunogen

Peptide with sequence CSRNYPQPRTEE, from the internal region of the protein sequence according to NP_001094345.1; NP_689811.2.

Biochem/physiol Actions

Membrane-associated RING-CH-type finger 10 (MARCH 10) may participate in the organization and maintenance of sperm flagella.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Membrane-Associated MARCH E3 Ligase Family: Emerging Roles in Immune Regulation.
Lin, et al.
Frontiers in Immunology, 10, 1751-1751 (2020)
Zihong Kang et al.
Theriogenology, 128, 8-16 (2019-02-04)
Membrane-associated ring-CH-type finger 1 (MARCH1), which mediates the ubiquitination of CD86 and MHC class II proteins, plays crucial roles in ruminant fecundity. To completely explore the functions of MARCH1 in goat reproduction, the mRNA expression of this gene were investigated
Ambroise Wonkam et al.
Clinical and translational medicine, 10(4), e152-e152 (2020-09-09)
Sickle cell anemia (SCA) is a clinically heterogeneous, monogenic disorder. Medical care has less-than-optimal impact on clinical outcomes in SCA in Africa due to several factors, including patient accessibility, poor access to resources, and non-availability of specific effective interventions for

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