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S9692

Sigma-Aldrich

SU 6656

≥98% (HPLC)

Synonym(s):

2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide

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About This Item

Empirical Formula (Hill Notation):
C19H21N3O3S
CAS Number:
330161-87-0
Molecular Weight:
371.45
MDL number:
MFCD10565928
UNSPSC Code:
12352200
PubChem Substance ID:
24278818
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

protect from light
under inert gas

color

orange-brown

solubility

DMSO: 12 mg/mL (orange solution)

storage temp.

−20°C

SMILES string

CN(C)S(=O)(=O)c1ccc2NC(=O)C(=C/c3cc4CCCCc4[nH]3)\c2c1

InChI

1S/C19H21N3O3S/c1-22(2)26(24,25)14-7-8-18-15(11-14)16(19(23)21-18)10-13-9-12-5-3-4-6-17(12)20-13/h7-11,20H,3-6H2,1-2H3,(H,21,23)/b16-10-

InChI key

LOGJQOUIVKBFGH-YBEGLDIGSA-N

Gene Information

human ... SRC(6714)

Biochem/physiol Actions

SU 6656 is a selective Src family kinase inhibitor. SU 6656 inhibits Src kinase in CD34 positively-selected umbilical cord blood cells.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Regeneration following spinal root avulsion is broadly unsuccessful despite the regenerative capacity of other PNS-located nerves. By combining focal laser lesioning to model root avulsion in zebrafish, time-lapse imaging, and transgenesis, we identify that regenerating DRG neurons fail to recapitulate
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