MSST0064
SILu™Prot Insulin, human
recombinant, expressed in Pichia pastoris, SIL MS Protein Standard, 15N -labeled
Synonym(s):
in situ Proximity Ligation Assay reagent, Insulin
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About This Item
UNSPSC Code:
23201100
NACRES:
NA.32
Recommended Products
recombinant
expressed in Pichia pastoris
Quality Level
Assay
≥95% (HPLC)
form
dry pellets
potency
≥97% (Heavy amino acids incorporation efficiency by MS)
suitability
suitable for mass spectrometry (standard)
UniProt accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
human ... INS(3630)
Related Categories
General description
SILu™ Prot Insulin is a recombinant, stable 15N isotope-labeled human Insulin Expressed in P. pastoris, it is designed to be used as an internal standard for bioanalysis of Insulin in mass-spectrometry. SILu™ Prot Insulin is a disulfate bonded hetero-dimer protein composed of two chains. Chain A of 21 amino acids and a thoretical amolecular mass of 2408.5; Chain B of 30 amino acids and a thoretical amolecular mass of 3468.7 (Note that Thr30 in chain B is not 15N labeled).
Biochem/physiol Actions
Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.
Sequence
A chain: GIVEQCCTSICSLYQLENYCN
B chain: FVNQHLCGSHLVEALYLVCGERGFFYTPKT
B chain: FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Physical form
Supplied as dried pellet from a solution containing 1% acetic acid.
Legal Information
This product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of Sigma-Aldrich Co. LLC
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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