BATF2 is a leucine zipper protein that may function as a transcription factor. Decreased BATF2 expression has been linked to the poor prognosis of oral tongue squamous cell and hepatocellular carcinomas. Rabbit anti-rabbit BATF2 antibody recognizes human and canine BATF2.
Immunogen
Synthetic peptide directed towards the middle region of human BATF2
Application
Rabbit anti-rabbit BATF2 antibody is suitable for western blot applications at a concentration of 0.25μg/ml.
Sequence
Synthetic peptide located within the following region: AQTAPPQPLELEHPTRGKLGSSPDNPSSALGLARLQSREHKPALSAATWQ
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
BATF2, also called SARI, is associated with several cancer types, and loss of BATF2 expression is frequently detected in aggressive and metastatic cancers. The expression of BATF2 was previously shown to slow the growth rate of malignant tumor cells injected
International journal of cancer, 128(4), 771-777 (2010-05-18)
Human BATF2, a basic leucine zipper protein, was recently detected in several normal immortalized cell lines but not in transformed cell lines. In addition, the expression of BATF2 also slowed the growth rate of malignant tumor cells injected into athymic
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