A3903

1-Aminocyclopropanecarboxylic acid

≥98% (TLC), powder, NMDA agonist

• Synonym(s): ACC, ACPC
• Empirical Formula (Hill Notation): C₄H₇NO₂
• CAS Number: 22059-21-8
• Molecular Weight: 101.10
• NACRES: NA.32
• PubChem Substance ID: 24890826
• UNSPSC Code: 12352209
• MDL number: MFCD00009944
• Beilstein/REAXYS Number: 2076413
• Assay: ≥98% (TLC)
• Form: powder
• Storage condition: (Keep container tightly closed in a dry and well-ventilated place.; Keep in a dry place.)

Properties

• Product Name: 1-Aminocyclopropanecarboxylic acid, ≥98% (TLC), powder
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• storage condition: (Keep container tightly closed in a dry and well-ventilated place.; Keep in a dry place.)
• color: white
• mp: 229-231 °C (lit.)
• solubility: water: 49.00-51.00 mg/mL, clear, colorless
• SMILES string: NC1(CC1)C(O)=O
• InChI: 1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)
• InChI key: PAJPWUMXBYXFCZ-UHFFFAOYSA-N
• Gene Information: human ... NARG2(79664) ; mouse ... NARG2(93697) ; rat ... LOC686240(686240), NARG2(691379)

Description

General description

Research area: Cell Signaling

1-Aminocyclopropanecarboxylic acid (ACC) is a non-proteinogenic amino acid[1] and is a member of 1-aminocycloalkanecarboxylic acids.

Application

1-Aminocyclopropanecarboxylic acid (ACC) has been used as a substrate for determining ACC deaminase activity to study the plant growth-promoting characteristics of endophytic isolates obtained from Pteris vittata roots[2], cucurbit seeds.[3] It has also been used as an ethylene precursor to study the effect of high ethylene concentration on lateral root density (LRD) in sorghum brown midrib (bmr) mutants.[4]

Biochem/physiol Actions

1-Aminocyclopropanecarboxylic acid (ACC) is a partial agonist acting at the N-methyl-D-aspartate (NMDA) receptor glycine modulatory site.[5] ACC serves as a bio-synthetic precursor for the plant hormone ethylene.[1] Therefore, it also plays a vital role in plant development.[2] ACC exhibits anticonvulsant, anxiolytic, anti-addictive, neuroprotective and antidepressant-like effects in rats and mice. ACC does not affect memory or learning processes.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves