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P6224

Sigma-Aldrich

TWEEN® 80

from non-animal source

Synonym(s):

POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80

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About This Item

CAS Number:
9005-65-6
MDL number:
MFCD00082107
UNSPSC Code:
12161900
NACRES:
NA.21

biological source

non-animal source

Quality Level

300

description

non-ionic

Assay

≥70.0% (GC)

form

viscous liquid

mol wt

micellar avg mol wt 79,000
average mol wt 1310

composition

Oleic acid, ≥70% (balance primarily linoleic, palmitic, and stearic acids)

aggregation number

60

CMC

0.012 mM (20-25°C)

transition temp

cloud point 65 °C

density

1.06 g/mL at 25 °C

HLB

15

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

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Application

Non-ionic detergent used for selective protein extraction and isolation of nuclei from mammalian cell lines.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

>235.4 °F - closed cup

Flash Point(C)

> 113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW1722
MKCT8229
MKCS7027
MKCS7026
MKCQ5691

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Jing-Yu Chen et al.
Journal of colloid and interface science, 526, 356-365 (2018-05-12)
Supramolecular assembly governs the formation and properties of many soft materials. Hence, it is significant to develop convenient approaches to control the assembly process. In this work, it is demonstrated that by using surfactants consisting of a sorbitan group (either
Martin L Cross et al.
Clinical and vaccine immunology : CVI, 16(9), 1378-1380 (2009-07-03)
Cultures of Mycobacterium bovis BCG, comprising predominantly single-cell bacilli, were prepared in broth without animal-derived reagents. When formulated into a vegetable-derived lipid matrix, the vaccine was stable in vitro and was immunogenic in vivo upon feeding it to mice. This
Syed A Sattar et al.
PloS one, 6(2), e17340-e17340 (2011-03-11)
Human noroviruses (HuNoV), a major cause of acute gastroenteritis worldwide, cannot be readily cultured in the lab. Therefore, a feline calicivirus (FCV) is often used as its surrogate to, among other things, test alcohol-based handrubs (ABHR). The more recent laboratory
Deepak Almeida et al.
Antimicrobial agents and chemotherapy, 53(10), 4178-4184 (2009-07-22)
To investigate the antagonism between isoniazid (INH) and rifampin (rifampicin) (RIF)-pyrazinamide (PZA) combination observed in Mycobacterium tuberculosis-infected mice, extensive pharmacokinetic studies of INH were performed and followed by experiments to assess the impact of increasing doses of INH on the
Hau-Ren Chen et al.
International journal of molecular sciences, 12(11), 8245-8258 (2011-12-17)
The separation of mercury ions from artificially contaminated water by the foam fractionation process using a biosurfactant (surfactin) and chemical surfactants (SDS and Tween-80) was investigated in this study. Parameters such as surfactant and mercury concentration, pH, foam volume, and
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