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Supelco

Lincomycin hydrochloride monohydrate

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C18H34N2O6S · HCl · H2O
CAS Number:
7179-49-9
Molecular Weight:
461.01
EC Number:
212-726-7
MDL number:
MFCD00167245
UNSPSC Code:
41116107
PubChem Substance ID:
329753904
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].[H]O[H].CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O

InChI

1S/C18H34N2O6S.ClH.H2O/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H;1H2/t9-,10-,11+,12-,13+,14-,15-,16-,18-;;/m1../s1

InChI key

LFZGYTBWUHCAKF-DCNJEFSFSA-N

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General description

Chemical structure: aminoglycoside
Lincomycin hydrochloride monohydrate, an antibiotic used in treating infections caused by staphylococcal, streptococcal, and Bacteroides fragilis. It is produced by Streptomyces lincolnensis.

Application

Lincomycin HCl monohydrate may have been used as reference standard for determination of antibiotics in novel tablet formulation using HPLC.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ6760
BCCH6692
BCBW4661
SZB8329XV
SZE8329X

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Eita Sasaki et al.
Journal of the American Chemical Society, 134(42), 17432-17435 (2012-09-20)
Lincomycin A is a potent antimicrobial agent noted for its unusual C1 methylmercapto-substituted 8-carbon sugar. Despite its long clinical history for the treatment of Gram-positive infections, the biosynthesis of the C(8)-sugar, methylthiolincosamide (MTL), is poorly understood. Here, we report our
P Calza et al.
Journal of mass spectrometry : JMS, 47(6), 751-759 (2012-06-19)
In this paper, a comprehensive study of the fate of an antibiotic, lincomycin, in the aquatic environment is presented. High-resolution mass spectrometry was employed to assess the evolution of the process over time. Formation of intermediate compounds was followed by
Phillip A Davis et al.
Photosynthesis research, 112(3), 153-161 (2012-06-15)
Plants use light to fix carbon through the process of photosynthesis but light also causes photoinhibition, by damaging photosystem II (PSII). Plants can usually adjust their rate of PSII repair to equal the rate of damage, but under stress conditions
Kazunori Miyata et al.
Photosynthesis research, 113(1-3), 165-180 (2012-07-17)
When visible light is excess, the photosynthetic machinery is photoinhibited. The extent of net photoinhibition of photosystem II (PSII) is determined by a balance between the rate of photodamage to D1 and some other PSII proteins and the rate of
C F Williams et al.
Journal of environmental quality, 41(5), 1473-1480 (2012-10-27)
The reuse of treated wastewater for groundwater recharge is an effective way to provide advanced treatment and water storage. Contaminants such as human drugs have been identified as a potential problem for use of this water. Gilbert, Arizona maintains a
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