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CBL1345

Sigma-Aldrich

Anti-Integrin α2 Antibody, clone HMα2

clone HMalpha2, Chemicon®, from hamster(Armenian)

Synonym(s):

CD49b

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

hamster (Armenian)

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

HMalpha2, monoclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

isotype

IgG

NCBI accession no.

NM_002203.3

UniProt accession no.

P17301

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGA2(3673)

Related Categories

General description

The complex of CD49b associated with CD29 (integrin beta1) is a receptor for laminin and collagen. This complex is expressed by some CD4-positive T cells, natural killer cells, epithelial cells and platelets.

Specificity

Specifically recognizes the 150 kDa mouse CD49b, also known as Integrin alpha2.

Application

Anti-Integrin α2 Antibody, clone HMα2 detects level of Integrin α2 & has been published & validated for use in FC, IF, IP, IH.
FlowCytometry: = .5 μg per 10e6 cells in 100 μL volume

Immunoprecipitation

Immunofluorescence

Immunohistochemistry

Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Physical form

Format: Purified
The affinity chromatography purified monoclonal is presented in phosphate buffered saline, pH 7.2, containing 0.09% sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.

Storage and Stability

Maintain at 2-8°C for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Carlos H F Chan et al.
PloS one, 2(12), e1353-e1353 (2007-12-27)
CEA and CEACAM6 are immunoglobulin family intercellular adhesion molecules that are up-regulated without structural mutations in approximately 70% of human cancers. Results in in vitro systems showing tumorigenic effects for these molecules suggest that this correlation could indicate an instrumental
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Naser, et al.
Annals of the New York Academy of Sciences, 1516, 175-187 (2022)
Helena P Felgueiras et al.
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