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218805

Sigma-Aldrich

Caspase-9 Substrate II, Colorimetric

The Caspase-9 Substrate II, Colorimetric serves as the substrate for Caspase-9.

Synonym(s):

Caspase-9 Substrate II, Colorimetric, Ac-LEHD- pNA, Ac-LEHD-pNA

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About This Item

Empirical Formula (Hill Notation):
C29H38N8O11
Molecular Weight:
674.66
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

A colorimetric substrate for caspase-9. Cleavage is monitored colorimetrically at ~405 nm.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Caspase-9
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Ac-Leu-Glu-His-Asp-pNA

Other Notes

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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