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L-907

Supelco

Lormetazepam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C16H12Cl2N2O2
CAS Number:
848-75-9
Molecular Weight:
335.18
EC Number:
200-659-6
MDL number:
MFCD00058578
UNSPSC Code:
41116107
PubChem Substance ID:
329817667
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CN1C(=O)C(O)N=C(c2ccccc2Cl)c3cc(Cl)ccc13

InChI

1S/C16H12Cl2N2O2/c1-20-13-7-6-9(17)8-11(13)14(19-15(21)16(20)22)10-4-2-3-5-12(10)18/h2-8,15,21H,1H3

InChI key

FJIKWRGCXUCUIG-UHFFFAOYSA-N

General description

Lormetazepam is a benzodiazepine with sedative-hypnotic, anxiolytic, anticonvulsant, and muscle relaxant effects. This certified solution standard is suitable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis. Lormetazepam is sold under trade names Loramet and Noctamid for treatment of insomnia.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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D Riemann et al.
Pharmacopsychiatry, 35(5), 165-174 (2002-09-19)
In recent years, sedating antidepressants have been increasingly used to treat primary insomnia. Up to now, only one open pilot study with trimipramine and one double-blind placebo-controlled study with doxepin have provided scientific support for this approach in treating primary
Musical hallucinations during a treatment with benzodiazepine.
François Curtin et al.
Canadian journal of psychiatry. Revue canadienne de psychiatrie, 47(8), 789-790 (2002-11-08)
Maurizio De Vanna et al.
Clinical drug investigation, 27(5), 325-332 (2007-04-25)
Sleep architecture changes with age, both in terms of efficiency and total duration of sleep. Hypnotic benzodiazepines promote rapid onset of sleep, uninterrupted sleep and longer duration of sleep in the absence of carryover sedation the following morning; therefore, these
W Dimpfel et al.
European journal of medical research, 3(10), 453-460 (1998-10-01)
Sleep in humans is classically assessed by recording a multichannel electroencephalogram (EEG) in connection with an electrooculogram (EOG) and an electromyogram (EMG). In general, human sleep is manually staged into 6 categories (from awake through REM sleep to stage 4
A Iudice et al.
International journal of clinical pharmacology and therapeutics, 40(7), 304-309 (2002-07-26)
To assess the residual effects of lormetazepam on daytime vigilance, psychomotor performance and simulated driving in adult healthy volunteers. Twelve subjects (7 women, 5 men), aged 27 - 38 years (mean 31). Subjects received lormetazepam 1 mg tablet and placebo
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