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904996

Sigma-Aldrich

Conjugated Polymer Nanoparticles incorporating iron oxide

fluorescence λem 680 nm, 100 μg/mL in H2O

Synonym(s):

Conjugated polymer nanoparticles, Fluorescent magnetic nanoparticles, Fluorescent nanoparticles, Magneto-conjugated polymer nanoparticles

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

form

nanoparticles

concentration

100 μg/mL in H2O

fluorescence

λem 680 nm

storage temp.

2-8°C

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Application

Iron oxide containing conjugated polymer nanoparticles are water-soluble nanoparticles compromising of light-emitting polymer and iron oxide. The presence of iron oxide in core makes these fluorescent nanoparticles distinctly different than conventional dyes as it allows their manipulation with a magnetic field. These nanoparticles possess a ′core-shell′ structure where light-emitting polymer and iron oxide are encapsulated in biocompatible surfactant.
The ′core-shell′ structure consisting of polymer and iron oxide in the core and the biocompatible surfactant in the surrounding shell allows easy covalently bonding of these nanoparticles with biomolecules such streptavidin, antibodies, proteins, nucleic acids, etc and make them suitable for the following applications:
  • Fluorescence Microscopy (high content screening, live cell tracking and 3-D cell imaging)
  • Immunohistochemistry and Immunocytochemistry
  • Flow Cytometry
  • Rapid Diagnostic Tests (RDTs)
  • Tissue Imaging
  • 2-Photon Imaging
  • NIR Imaging

Storage and Stability

The robustness of CPNs enables them to be used under high intensity illumination and in extreme experimental conditions if required, while their 24-month shelf-life permits convenient storage at ambient temperatures.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Loading Graphene Quantum Dots into Optical-Magneto Nanoparticles for Real-Time Tracking In Vivo
Wang Y, et al.
Materials, 12(13), 2191-2191 (2019)
General synthesis of high-performing magneto-conjugated polymer core-shell nanoparticles for multifunctional theranostics
Yan H, et al.
Nano Research, 10(2), 704-717 (2017)
General synthesis of high-performing magneto-conjugated polymer core?shell nanoparticles for multifunctional theranostics
H Yan et al.
Nano Research, 10, 704-704 (2017)
Fluorescent magnetic nanoparticles for biomedical applications
Chekina N, et al.
Journal of Materials Chemistry, 21(21), 7630-7639 (2011)
Philip Howes et al.
Journal of the American Chemical Society, 132(28), 9833-9842 (2010-06-25)
Hybrid nanoparticles which incorporate multiple functionalities, such as fluorescence and magnetism, can exhibit enhanced efficiency and versatility by performing several tasks in parallel. In this study, magnetic-fluorescent semiconductor polymer nanospheres (MF-SPNs) have been synthesized by encapsulation of hydrophobic conjugated polymers

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