677264

APhos

95%

• Synonym(s): (4-(N,N-Dimethylamino)phenyl)di-tert-butyl phosphine, A-^taPhos, [4-(Dimethylamino)phenyl]bis(tert-butyl)phosphine
• Empirical Formula (Hill Notation): C₁₆H₂₈NP
• CAS Number: 932710-63-9
• Molecular Weight: 265.37
• MDL number: MFCD09265102
• UNSPSC Code: 12352116
• PubChem Substance ID: 24885360
• NACRES: NA.22

Properties

• Assay: 95%
• form: solid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; reagent type: ligand; reaction type: Cross Couplings
• mp: 57-61 °C
• functional group: phosphine
• SMILES string: CN(C)c1ccc(cc1)P(C(C)(C)C)C(C)(C)C
• InChI: 1S/C16H28NP/c1-15(2,3)18(16(4,5)6)14-11-9-13(10-12-14)17(7)8/h9-12H,1-8H3
• InChI key: IQTHEAQKKVAXGV-UHFFFAOYSA-N

Description

Application

Ligand used to prepare a palladium dichloride catalyst (678740) on treatment with PdCl₂(COD). The catalyst effectively cross-couples aryl boronic acids with heteroaryl chlorides.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P305 + P351 + P338 - P310
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8B - Non-combustible, corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable