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254819

Sigma-Aldrich

Hydroquinidine hydrochloride

98%

Synonym(s):

Dihydroquinidine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C20H26N2O2 · HCl
CAS Number:
1476-98-8
Molecular Weight:
362.89
EC Number:
216-024-1
MDL number:
MFCD00135598
UNSPSC Code:
12352005
PubChem Substance ID:
24855267
NACRES:
NA.22

Quality Level

100

Assay

98%

form

powder

optical activity

[α]20/D +185.2°, c = 1.3 in H2O

mp

277-279 °C (lit.)

SMILES string

Cl.CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c3ccnc4ccc(OC)cc34

InChI

1S/C20H26N2O2.ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3;1H/t13-,14-,19+,20-;/m0./s1

InChI key

MULXTQKDWYBJMO-VJAUXQICSA-N

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fiorenzo Gaita et al.
Journal of the American College of Cardiology, 43(8), 1494-1499 (2004-04-20)
The purpose of this study was to evaluate the efficacy of various antiarrhythmic drugs at prolonging the QT interval into the normal range and preventing ventricular arrhythmias in patients with short QT syndrome. Short QT syndrome is a recently described
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Atmospheric pressure (AP) matrix-assisted laser desorption/ionization (MALDI) is known to suffer from poor ion transfer efficiencies as compared to conventional vacuum MALDI (vMALDI). To mitigate these issues, a new AP-MALDI ion source utilizing a coaxial gas flow was developed. Nitrogen
Saleem Aladaileh et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 148(4), 470-480 (2007-10-24)
Phenoloxidase (PO) activity was studied in Sydney rock oysters (Saccostrea glomerata). As in other molluscs, PO was found to exist as a pro-enzyme (proPO) in hemocytes. ProPO could be activated to PO by exogenous proteases (trypsin and chymotrypsin), exposure of
C K Mannesse et al.
Nederlands tijdschrift voor geneeskunde, 147(13), 585-587 (2003-04-19)
Two women, aged 77 and 73 years, and one man, aged 71 years, were admitted because of a serious adverse drug reaction (ADR). The first woman had a probable adverse drug reaction caused by digoxin after the addition of a
Short QT syndrome in infancy. Therapeutic drug monitoring of hydroquinidine in a newborn infant.
Elisa Pirro et al.
British journal of clinical pharmacology, 72(6), 982-984 (2011-06-29)
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