Skip to Content
Merck
All Photos(1)

Documents

228907

Sigma-Aldrich

2-Nitrobenzenesulfonamide

98%

Synonym(s):

NSC 23381, NSC 629275

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
O2NC6H4SO2NH2
CAS Number:
5455-59-4
Molecular Weight:
202.19
MDL number:
MFCD00009807
UNSPSC Code:
12352100
PubChem Substance ID:
24853717
NACRES:
NA.22

Quality Level

100

Assay

98%

mp

190-192 °C (lit.)

SMILES string

NS(=O)(=O)c1ccccc1[N+]([O-])=O

InChI

1S/C6H6N2O4S/c7-13(11,12)6-4-2-1-3-5(6)8(9)10/h1-4H,(H2,7,11,12)

InChI key

GNDKYAWHEKZHPJ-UHFFFAOYSA-N

Application

Reactant involved in synthesis of:
  • Cyclic nitrogen compounds via intramolecular hydroamination
  • Pentacyclic lycopodium alkaloid huperzine-Q
  • Pyrrolidines
  • Intermolecular C-H insertion reactions

Reactant involved in intermolecular amination of allyl alcohols

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Y Hidai et al.
Chemical & pharmaceutical bulletin, 48(10), 1570-1576 (2000-10-25)
Total synthesis of spider toxins HO-416b (1) and Agel-489 (2) was accomplished using the 2-nitrobenzenesulfonamide (Ns) group as both a protecting and activating group. In this strategy, the C-N bonds were constructed by alkylation of sulfonamides with alkyl halides or

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service