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130591

Sigma-Aldrich

Tris(2-butoxyethyl) phosphate

94%

Synonym(s):

Phosphoric acid tris(2-butoxyethyl) ester

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About This Item

Linear Formula:
[CH3(CH2)3OCH2CH2O]3P(O)
CAS Number:
Molecular Weight:
398.47
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor density

13.7 (vs air)

vapor pressure

0.03 mmHg ( 150 °C)

Assay

94%

form

liquid

refractive index

n20/D 1.438 (lit.)

bp

215-228 °C/4 mmHg (lit.)

density

1.006 g/mL at 25 °C (lit.)

SMILES string

CCCCOCCOP(=O)(OCCOCCCC)OCCOCCCC

InChI

1S/C18H39O7P/c1-4-7-10-20-13-16-23-26(19,24-17-14-21-11-8-5-2)25-18-15-22-12-9-6-3/h4-18H2,1-3H3

InChI key

WTLBZVNBAKMVDP-UHFFFAOYSA-N

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General description

Tris(2-butoxyethyl) phosphate is an organic flame retardant. It shows PXR agonistic activity. Tris(2-butoxyethyl) phosphate was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.

Application

  • Monitoring of OPFRs in Environmental Samples: A novel method for the rapid monitoring of organophosphate flame retardants (OPFRs) such as tris(2-butoxyethyl) phosphate in environmental samples was developed, utilizing liquid-liquid extraction and gas chromatography-mass spectrometry. This method aids in assessing the biodegradation of such compounds effectively (Losantos et al., 2024).
  • Presence in Landfill Soil: A case study explored the prevalence of tris(2-butoxyethyl) phosphate in inert landfill soil, highlighting the environmental impact and challenges in managing the disposal of materials containing this chemical (Stelzer et al., 2023).
  • Bioremediation of Contaminated Soil: The study demonstrated that earthworms could enhance the bioremediation of soil contaminated with tris(2-butoxyethyl) phosphate by facilitating the release of degrading microbes, providing a sustainable method to mitigate environmental pollution (Wu et al., 2023).
  • Assessment of Human Exposure to Household Chemicals: Research utilized on-line solid-phase extraction coupled with liquid chromatography-tandem mass spectrometry to assess human exposure to chemicals including tris(2-butoxyethyl) phosphate, commonly found in personal care and household products. This study aids in understanding population-level exposure dynamics (Senta et al., 2022).
  • SVOCs Transmission from Indoors to Outdoors: Investigation into how textile washing conveys semi-volatile organic compounds (SVOCs) like tris(2-butoxyethyl) phosphate from indoor environments to outdoors, using a residential multimedia model to predict environmental dispersion and impact (Kvasnicka et al., 2021).

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

318.2 °F - closed cup

Flash Point(C)

159 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Elke Fries et al.
Journal of environmental monitoring : JEM, 5(2), 346-352 (2003-05-06)
The behaviour of the three organophosphate esters tributyl phosphate (TBP), tris(2-chloroethyl)phosphate (TCEP) and tris(2-butoxyethyl)phosphate (TBEP) during infiltration of river water to ground water has been investigated. The monitoring site is the Oder River and the adjacent Oderbruch aquifer. From March
S Laham et al.
American Industrial Hygiene Association journal, 46(8), 442-448 (1985-08-01)
The response of the peripheral nervous system to various dose levels of tributoxyethyl phosphate (TBOP) was investigated in Sprague-Dawley rats. Groups of randomized female and male rats (10 rats/gender/dose level) were administered a single oral dose of TBOP (1.0 to
I H Benedek et al.
Journal of pharmaceutical sciences, 74(8), 837-840 (1985-08-01)
Drug-serum protein binding was evaluated in genetically obese Zucker rats, their lean littermates, and lean Sprague-Dawley rats. The free fraction (fp) of phenytoin was significantly higher in the obese rat (fp = 0.177) compared to its lean littermate (fp =
Zhihua Han et al.
Aquatic toxicology (Amsterdam, Netherlands), 150, 175-181 (2014-04-02)
The flame retardant tris(2-butoxyethyl) phosphate (TBEP) is a frequently detected contaminant in the environment, wildlife and human milk. The potentially toxic effects of TBEP and their underlying molecular mechanisms have not been elucidated. Here, zebrafish embryos were exposed to different
E Fries et al.
Journal of environmental monitoring : JEM, 3(6), 621-626 (2002-01-12)
The present investigation was carried out to quantify the three organophosphate esters, tributyl phosphate (TBP), tris(2-chloroethyl) phosphate(TCEP) and tris(2-butoxyethyl) phosphate(TBEP), in river, rain and ground water obtained from several locations in Germany, and to compare the data with those obtained

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