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129887

Sigma-Aldrich

N-Methylisatoic anhydride

technical, 90%

Synonym(s):

1-Methyl-1H -benzo[d ][1,3]oxazine-2,4-dione, 1-Methyl-4H -3,1-benzoxazine-2,4(1H )dione

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About This Item

Empirical Formula (Hill Notation):
C9H7NO3
CAS Number:
Molecular Weight:
177.16
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

vapor density

6.1 (vs air)

Quality Level

grade

technical

Assay

90%

mp

165 °C (dec.) (lit.)

SMILES string

CN1C(=O)OC(=O)c2ccccc12

InChI

1S/C9H7NO3/c1-10-7-5-3-2-4-6(7)8(11)13-9(10)12/h2-5H,1H3

InChI key

KJMRWDHBVCNLTQ-UHFFFAOYSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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G Knipping et al.
The International journal of biochemistry, 25(4), 505-511 (1993-04-01)
1. To investigate whether a direct protein-protein interaction between apoA-I and lecithin:cholesterol acyltransferase (LCAT) is necessary for the activation of the enzyme, apoA-I was labelled with N-methylisatoic anhydride at lysine residues. The intermolecular resonance energy transfer from tryptophan residues of
Sanjaya C Abeysirigunawardena et al.
Nature communications, 8(1), 492-492 (2017-09-10)
Assembly of 30S ribosomes involves the hierarchical addition of ribosomal proteins that progressively stabilize the folded 16S rRNA. Here, we use three-color single molecule FRET to show how combinations of ribosomal proteins uS4, uS17 and bS20 in the 16S 5'
Erich Smith-Peter et al.
RNA biology, 12(12), 1372-1382 (2015-09-26)
Riboswitches regulate gene expression by rearranging their structure upon metabolite binding. The lysine-sensing lysC riboswitch is a rare example of an RNA aptamer organized around a 5-way helical junction in which ligand binding is performed exclusively through nucleotides located at
Kady-Ann Steen et al.
Journal of the American Chemical Society, 134(32), 13160-13163 (2012-08-03)
Many RNA structures are composed of simple secondary structure elements linked by a few critical tertiary interactions. SHAPE chemistry has made interrogation of RNA dynamics at single-nucleotide resolution straightforward. However, de novo identification of nucleotides involved in tertiary interactions remains
Colby D Stoddard et al.
RNA (New York, N.Y.), 14(4), 675-684 (2008-02-13)
Riboswitches are highly structured cis-acting elements located in the 5'-untranslated region of messenger RNAs that directly bind small molecule metabolites to regulate gene expression. Structural and biochemical studies have revealed riboswitches experience significant ligand-dependent conformational changes that are coupled to

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