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14079

Sigma-Aldrich

Succinic acid

puriss. p.a., ACS reagent, ≥99.5% (T)

Synonym(s):

Butanedioic acid

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About This Item

Linear Formula:
HOOCCH2CH2COOH
CAS Number:
Molecular Weight:
118.09
Beilstein:
1754069
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent
puriss. p.a.

Quality Level

Assay

≥99.5% (T)

impurities

≤0.001% total nitrogen (N)

ign. residue

≤0.02%

bp

235 °C (lit.)

mp

184-186 °C (lit.)
185-191 °C

solubility

methanol: soluble 0.4 g/10 mL

anion traces

chloride (Cl-): ≤10 mg/kg
phosphate (PO43-): ≤10 mg/kg
sulfate (SO42-): ≤30 mg/kg

cation traces

Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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Application

Succinic acid may be employed in the following studies:

  • Surfactant/detergent extender/foaming agent
  • As ion chelator in the electroplating process
  • As a precursor for various industrially important chemicals such as adipic acid, 1,4-butanediol, tetrahydrofuran, N-methyl pyrrolidinone, 2-pyrrolidinone, succinate salts, and γ-butyrolactone
  • Synthesis of biodegradable polymers such as polybutyrate succinate (PBS) and polyamides.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Virendra Gajbhiye et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(4-5), 668-679 (2013-01-10)
The present investigation was aimed at exploring dual targeting of anti-HIV drug, zidovudine (ZDV) via sialic acid conjugated-mannosylated poly(propyleneimine) (PPI) dendritic nano-constructs. Fourth generation PPI dendrimers, sialic acid conjugated PPI dendrimers (SPPI), mannose conjugated PPI dendrimers (MPPI) and dual ligand
Song H and Lee SY.
Enzyme and Microbial Technology, 39(3), 352-361 (2006)
P C Lee et al.
Biotechnology and bioengineering, 72(1), 41-48 (2000-11-21)
Succinic acid was produced by fermentation of Anaerobiospirillum succiniciproducens using glycerol as a carbon source. When cells were anaerobically cultured in a medium containing 6.5 g/L glycerol, a high succinic acid yield (133%) was obtained while avoiding the formation of
Biotechnology of succinic acid production and markets for derived industrial products.
Zeikus JG, et al.
Applied Microbiology and Biotechnology, 51(5), 545-552 (1999)
G M Tannahill et al.
Nature, 496(7444), 238-242 (2013-03-29)
Macrophages activated by the Gram-negative bacterial product lipopolysaccharide switch their core metabolism from oxidative phosphorylation to glycolysis. Here we show that inhibition of glycolysis with 2-deoxyglucose suppresses lipopolysaccharide-induced interleukin-1β but not tumour-necrosis factor-α in mouse macrophages. A comprehensive metabolic map

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