361615

Palmatine chloride hydrate

97%

• Synonym(s): 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium chloride hydrate (1:1:1)
• Empirical Formula (Hill Notation): C₂₁H₂₂ClNO₄ · xH₂O
• CAS Number: 171869-95-7
• Molecular Weight: 387.86 (anhydrous basis)
• MDL number: MFCD00150276
• UNSPSC Code: 12352100
• PubChem Substance ID: 24862239
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• impurities: ~1.5 mol/mol methanol
• mp: 206-207 °C (dec.) (lit.)
• SMILES string: [Cl-].[H]O[H].COc1cc2CC[n+]3cc4c(OC)c(OC)ccc4cc3-c2cc1OC
• InChI: 1S/C21H22NO4.ClH.H2O/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;;/h5-6,9-12H,7-8H2,1-4H3;1H;1H2/q+1;;/p-1
• InChI key: PIQNSCSNSSZUIT-UHFFFAOYSA-M

Description

General description

Palmatine chloride hydrate (Palmatine) is an alkaloid. It is a potential phototoxin, and exhibits low quantum yields for fluorescence. Normal Raman spectra and DFT calculations of palmatine chloride hydrate is reported.

Application

Palmatine chloride hydrate (Palmatine) is suitable for use:

• as alkaloid standard in the method validation for determination of berberine, hydrastine and canadine in goldenseal (Hydrastis canadensis L.) root powder
• in the preparation of 8-heteroaryl-7,8-dihydroprotoberberine
• in a study to investigate the FT-Raman and surface-enhanced Raman scattering (SERS) spectra of three related alkaloid dyes, namely palmatine, jatrorrhizine and coptisine

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H332,H315,H319
• Precautionary Statements: P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves