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195022

Sigma-Aldrich

2-Ethyl-2-phenylmalonamide monohydrate

99%

Synonym(s):

PEMA

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About This Item

Linear Formula:
C6H5C(C2H5)(CONH2)2·H2O
CAS Number:
80866-90-6
Molecular Weight:
224.26
MDL number:
MFCD00149557
UNSPSC Code:
12352100
PubChem Substance ID:
24851668
NACRES:
NA.22

Assay

99%

form

solid

mp

120 °C (dec.) (lit.)

functional group

amide

SMILES string

O.CCC(C(N)=O)(C(N)=O)c1ccccc1

InChI

1S/C11H14N2O2.H2O/c1-2-11(9(12)14,10(13)15)8-6-4-3-5-7-8;/h3-7H,2H2,1H3,(H2,12,14)(H2,13,15);1H2

InChI key

FZSBWHZDTUPYRX-UHFFFAOYSA-N

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Application

2-Ethyl-2-phenylmalonamide monohydrate was used in quantification of 2-ethyl-2-phenylmalonamide in serum of epilepsy patients by gas liquid chromatography.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
MKBR1275V
04109HJ
8016LJ
10008PG

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D Haidukewych et al.
Clinical chemistry, 26(11), 1537-1539 (1980-10-01)
We describe a procedure for determining 2-ethyl-2-phenylmalonamide (I) in serum of epilepsy patients dosed with primidone (II) for seizure control, by extracting the sample with chloroform under basic conditions, with use of an internal standard, 2-ethyl-2-(p-tolyl)malonamide, and without derivative formation.
Jane Bryant et al.
Biomaterials, 35(31), 8887-8894 (2014-07-30)
Human islet cell transplantation is a promising treatment for type 1 diabetes; however, long-term donor-specific tolerance to islet allografts remains a clinically unmet goal. We have previously shown that recipient infusions of apoptotic donor splenocytes chemically treated with 1-ethyl-3-(3'-dimethylaminopropyl)-carbodiimide (donor ECDI-SP)
Ludmila Mut et al.
Biomedical chromatography : BMC, 29(6), 935-952 (2014-11-18)
An automated multi-analyte screening method for the identification and quantification of 92 drugs and metabolites based on on-line solid-phase extraction-high-performance liquid chromatography-diode array detection technique was developed and successfully validated. In addition, a database with 870 entries including UV-spectra, relative/retention
Eike Müller et al.
Biomaterials, 53, 709-715 (2015-04-22)
Deciphering exogenous cues that determine stem cell fate decisions is a persisting challenge of cell biology and bioengineering. In an effort to unravel the role of spatial constraints in the cell-instructive characteristics of bone marrow microenvironments, murine hematopoietic stem and
Lionel Tortolano et al.
Journal of biomedical materials research. Part A, 103(12), 3843-3851 (2015-06-27)
The aim of this study is to investigate in vitro interactions between hydrophobic acrylate intraocular lenses (IOLs) and their biological environment. The influence of lens chemical composition and aging on fibronectin (FN) adsorption and on IOLs cytotoxicity on human lens

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