143758

3,4-Dimethoxybenzaldehyde

99%

• Synonym(s): Methylvanillin, NSC 24521, NSC 8500, Vanillin methyl ether, Veratraldehyde
• Linear Formula: (CH₃O)₂C₆H₃CHO
• CAS Number: 120-14-9
• Molecular Weight: 166.17
• Beilstein: 473899
• EC Number: 204-373-2
• MDL number: MFCD00003363
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848608
• NACRES: NA.22

Properties

• Assay: 99%
• form: solid
• bp: 281 °C (lit.)
• mp: 40-43 °C (lit.)
• solubility: alcohol: freely soluble; diethyl ether: freely soluble; water: slightly soluble (hot)
• SMILES string: [H]C(=O)c1ccc(OC)c(OC)c1
• InChI: 1S/C9H10O3/c1-11-8-4-3-7(6-10)5-9(8)12-2/h3-6H,1-2H3
• InChI key: WJUFSDZVCOTFON-UHFFFAOYSA-N

Description

General description

3,4-Dimethoxybenzaldehyde forms 1:1 inclusion complexes with cyclodextrins. It reacts with 3-acetyl-2,5-dimethythiophene to yield chalcone dye, (2E)-3-(3,4-Dimethoxyphenyl)-1-(2,5-dimethylthiophen-3-yl)prop-2-en-1-one.

Application

3,4-Dimethoxybenzaldehyde was used in the preparation of 4-chloromethyl-2-(dimethoxyphenyl)-1,3-dioxolane. It was used in the synthesis of (+)-lithospermic acid, having anti-HIV activity.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves