139181
Bromodichloromethane
≥97%
Synonym(s):
Dichlorobromomethane
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About This Item
Linear Formula:
BrCHCl2
CAS Number:
Molecular Weight:
163.83
Beilstein:
1697005
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
≥97%
form
liquid
contains
potassium carbonate as stabilizer
refractive index
n20/D 1.497 (lit.)
bp
87 °C (lit.)
mp
−55 °C (lit.)
solubility
water: insoluble
density
1.98 g/mL at 25 °C (lit.)
functional group
bromo
SMILES string
ClC(Cl)Br
InChI
1S/CHBrCl2/c2-1(3)4/h1H
InChI key
FMWLUWPQPKEARP-UHFFFAOYSA-N
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Application
Bromodichloromethane was used to investigate the in vivo genotoxicity of chlorodibromomethane, bromodichloromethane and bromoform in mice.
Biochem/physiol Actions
Bromodichloromethane (BDCM) induces steatohepatitic injury in human liver. BDCM induces the cell proliferation in different tissues and kidney damage by renal tuble cell proliferation in male F344 rats.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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K J Stocker et al.
Mutagenesis, 12(3), 169-173 (1997-05-01)
Chlorination of drinking water results in the formation of chlorodibromomethane, bromodichloromethane and bromoform. These trihalomethanes have all shown evidence of genotoxicity in bacterial and mammalian cell systems in vitro and some evidence of carcinogenicity in rodents. Chlorodibromomethane and bromodichloromethane have
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Suvarthi Das et al.
American journal of physiology. Gastrointestinal and liver physiology, 305(12), G950-G963 (2013-10-26)
Recent studies indicate that metabolic oxidative stress, autophagy, and inflammation are hallmarks of nonalcoholic steatohepatitis (NASH) progression. However, the molecular mechanisms that link these important events in NASH remain unclear. In this study, we investigated the mechanistic role of purinergic
Teresa L Leavens et al.
Toxicological sciences : an official journal of the Society of Toxicology, 99(2), 432-445 (2007-07-28)
Exposure to bromodichloromethane (BDCM), one of the most prevalent disinfection byproducts in drinking water, can occur via ingestion of water and by dermal absorption and inhalation during activities such as bathing and showering. The objectives of this research were to
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Today's developed world faces a major public health challenge in the rise in the obese population and the increased incidence in fatty liver disease. There is a strong association among diet induced obesity, fatty liver disease and development of nonalcoholic
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