1365065

Levothyroxine sodium

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Levothyroxine sodium hydrate, 3,3′,5,5′-Tetraiodo-L-thyronine monosodium salt hydrate, L-Thyroxin monosodium salt hydrate, Sodium O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine hydrate
• Empirical Formula (Hill Notation): C₁₅H₁₀I₄NNaO₄ · xH₂O
• CAS Number: 25416-65-3
• Molecular Weight: 798.85 (anhydrous basis)
• MDL number: MFCD06408007
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750053
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: levothyroxine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O
• InChI: 1S/C15H11I4NO4.Na.H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;1H2/q;+1;/p-1/t12-;;/m0../s1
• InChI key: ANMYAHDLKVNJJO-LTCKWSDVSA-M
• Gene Information: human ... THRA(7067) , THRB(7068)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Levothyroxine sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H372
• Precautionary Statements: P260 - P264 - P270 - P314 - P501
• Hazard Classifications: STOT RE 1
• Target Organs: Thyroid,Cardio-vascular system,Kidney
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable