V7127

D-Val-Leu-Lys p-nitroanilide dihydrochloride

plasmin substrate, chromogenic, ≥98% (HPLC), powder

• Synonym(s): D-Val-Leu-Lys p-nitroanilide
• Empirical Formula (Hill Notation): C₂₃H₃₈N₆O₅ · 2HCl
• Molecular Weight: 551.51
• UNSPSC Code: 12352204
• PubChem Substance ID: 24900765
• NACRES: NA.32

Properties

• Product Name: D-Val-Leu-Lys p-nitroanilide dihydrochloride, plasmin substrate
• Quality Level: 200
• Assay: ≥98% (HPLC)
• form: powder
• solubility: water: 50 mg/mL, clear, light yellow
• storage temp.: −20°C
• SMILES string: Cl.[N+](=O)([O-])c1ccc(cc1)NC(=O)C(NC(=O)C(NC(=O)C(N)C(C)C)CC(C)C)CCCCN
• InChI: 1S/C23H38N6O5.ClH/c1-14(2)13-19(28-23(32)20(25)15(3)4)22(31)27-18(7-5-6-12-24)21(30)26-16-8-10-17(11-9-16)29(33)34;/h8-11,14-15,18-20H,5-7,12-13,24-25H2,1-4H3,(H,26,30)(H,27,31)(H,28,32);1H
• InChI key: ITWYYDDNWFVYSU-UHFFFAOYSA-N

Description

Application

D-Val-Leu-Lys p-nitroanilide dihydrochloride has been used:

• as substrate to measure the activity of plasminogen activator by a chromogenic assay
• as a p-nitroanilide (pNA) substrate to measure the specific activities of serine protease isoforms in Gloydius intermedius venom
• as a substrate in total plasmin assay using milk/cream samples

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H312 + H332,H315,H319,H335,H361
• Precautionary Statements: P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves