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V7127

Sigma-Aldrich

D-Val-Leu-Lys p-nitroanilide dihydrochloride

plasmin substrate, chromogenic, ≥98% (HPLC), powder

Synonym(s):

D-Val-Leu-Lys p-nitroanilide

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About This Item

Empirical Formula (Hill Notation):
C23H38N6O5 · 2HCl
Molecular Weight:
551.51
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

Product Name

D-Val-Leu-Lys p-nitroanilide dihydrochloride, plasmin substrate

Assay

≥98% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear, light yellow

storage temp.

−20°C

SMILES string

Cl.[N+](=O)([O-])c1ccc(cc1)NC(=O)C(NC(=O)C(NC(=O)C(N)C(C)C)CC(C)C)CCCCN

InChI

1S/C23H38N6O5.ClH/c1-14(2)13-19(28-23(32)20(25)15(3)4)22(31)27-18(7-5-6-12-24)21(30)26-16-8-10-17(11-9-16)29(33)34;/h8-11,14-15,18-20H,5-7,12-13,24-25H2,1-4H3,(H,26,30)(H,27,31)(H,28,32);1H

InChI key

ITWYYDDNWFVYSU-UHFFFAOYSA-N

Application

D-Val-Leu-Lys p-nitroanilide dihydrochloride has been used:
  • as substrate to measure the activity of plasminogen activator by a chromogenic assay
  • as a p-nitroanilide (pNA) substrate to measure the specific activities of serine protease isoforms in Gloydius intermedius venom
  • as a substrate in total plasmin assay using milk/cream samples

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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