SCP0247
Factor VIIa substrate
≥95% (HPLC), lyophilized
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About This Item
Empirical Formula (Hill Notation):
C30H42N7O7S1
Molecular Weight:
644.76
UNSPSC Code:
12352204
NACRES:
NA.32
Recommended Products
product name
Factor VIIa substrate,
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥72%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
MeSO2-Cha-Abu-Arg-AFC
Application
Factor VIIa is a serine protease involved in the blood coagulation cascade. The activity of Factor VIIa can be assayed with chromogenic substrate MeSO2-Cha-Abu-Arg-pNA or the flourogenic substrate MeSO2-Cha-Abu-Arg-AFC.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Giuseppe Lippi et al.
Seminars in thrombosis and hemostasis, 35(1), 9-22 (2009-03-25)
Hemostasis is traditionally defined as the physiologic process whereby bleeding is antagonized and possibly stopped to minimize blood loss. The first medical description of the clinical and inherited features of hemostasis can be dated back more than 1000 years, when
Flora Peyvandi et al.
Thrombosis and haemostasis, 88(5), 750-755 (2002-11-13)
Factor VII (FVII) requires the cleavage of an internal peptide bond and the association with tissue factor (TF) to attain its fully active FVIIa conformation. This event alone leaves FVIIa in a zymogen-like state of relatively low specific activity. The
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