Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

SCP0101

Sigma-Aldrich

Caspase Substrate

≥95% (HPLC), lyophilized

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C35H40N6O11
Molecular Weight:
720.73
UNSPSC Code:
12352202
NACRES:
NA.32

product name

Caspase Substrate,

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥80%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Z-Tyr-Val-Ala-Asp-pNA

Application

Z-YVAD-pNa (Z-Tyr-Val-Ala-Asp-pNA) is used as a caspase 1 substrate.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A Eckert et al.
Journal of neuroscience research, 64(2), 183-192 (2001-04-05)
The Swedish double mutation (KM670/671NL) of amyloid precursor protein (APPsw) is associated with early-onset familial Alzheimer's disease (FAD) and results in from three- to sixfold increased beta-amyloid production. The goal of the present study was to elucidate the effects of
G P McStay et al.
Cell death and differentiation, 15(2), 322-331 (2007-11-03)
Caspases orchestrate the controlled demise of a cell after an apoptotic signal through specific protease activity and cleavage of many substrates altering protein function and ensuring apoptosis proceeds efficiently. Comparing a variety of substrates of each apoptotic caspase (2, 3
Natasha Ann Pereira et al.
Biochemical and biophysical research communications, 377(3), 873-877 (2008-11-04)
Many designated substrates and inhibitors have been widely used to investigate the roles of caspases in apoptotic death during mammalian cell culture. However, the specificities of these substrates and inhibitors have not been systematically evaluated. As a result, conclusions on

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service