SCP0077
Caspase 2 Substrate (ICH-1), chromogenic
≥90% (HPLC), lyophilized
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C29H41N7O12
Molecular Weight:
679.68
UNSPSC Code:
12352202
NACRES:
NA.32
Recommended Products
product name
Caspase 2 Substrate (ICH-1), chromogenic, ≥90% (HPLC)
Assay
≥90% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Ac-Val-Asp-Val-Ala-Asp-pNA
Application
Caspase 2 is a cysteine protease that is potentially involved in cell cycle regulation and tumour suppression may be detected using peptides that contain the pentapeptide VDVAD such as the chromogenic and fluorogenic substrates: Ac-VDVAD-pNa (Acetyl-Val-Asp-Val-Ala-Asp-p- nitroanalide), chromogenic and MCA-VDVADGW-DNP-K-NH2, fluorogenic.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis.
Tang Y, Wells JA, Arkin MR.
The Journal of Biological Chemistry, 286, 31147-34154 (2011)
Tanja Kitevska et al.
Apoptosis : an international journal on programmed cell death, 14(7), 829-848 (2009-05-30)
The caspases are an evolutionarily conserved family of cysteine proteases, with essential roles in apoptosis or inflammation. Caspase-2 was the second caspase to be cloned and it resembles the prototypical nematode caspase CED-3 more closely than any other mammalian protein.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service