DMSO is the only solvent that is validated.
R0908
R1881
≥98% (HPLC), Androgen receptor agonist, powder
Synonym(s):
(17b)-17-Hydroxy-17-methyl-Estra-4,9,11-trien-3-one, Methyltrienolone, Metribolone, NSC 92858, RU 1881
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About This Item
Empirical Formula (Hill Notation):
C19H24O2
CAS Number:
Molecular Weight:
284.39
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Pricing and availability is not currently available.
Product Name
R1881, ≥98% (HPLC)
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D -48 to -68°
drug control
USDEA Schedule IIIN; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
color
light yellow to yellow
solubility
DMSO: ≥10 mg/mL
storage temp.
2-8°C
SMILES string
C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3C=C[C@]12C
InChI
1S/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1
InChI key
CCCIJQPRIXGQOE-XWSJACJDSA-N
Biochem/physiol Actions
Androgen receptors (ARs) are nuclear hormone receptors/transcription factors. R1881, also known as methyltrienolone, is a synthetic androgen. It is the gold standard AR agonist.
R1881 (methyltrienolone) is a potent synthetic androgen.
Features and Benefits
This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥97% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form solid |
| drug control USDEA Schedule IIIN; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada | drug control USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada | drug control - | drug control - |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: ≥10 mg/mL | solubility DMSO: 5 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear | solubility H2O: >10 mg/mL |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Hello, I’d like to treat my organoids in vitro with R1881. In previous experiments, they were quite sensitive to DMSO toxicity. Could you please tell me if R1881 can be dissolved in another solvent, such as ethanol or methanol?
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