PZ0297

PF-06305591 dihydrate

≥98% (HPLC)

• Synonym(s): (αR,βS)-β-Amino-6-(1,1-dimethylethyl)-α-methyl-1H-benzimidazole-2-propanamide dihydrate
• Empirical Formula (Hill Notation): C₁₅H₂₂N₄O · 2H₂O
• CAS Number: 1449473-97-5
• Molecular Weight: 310.39
• UNSPSC Code: 12352200
• PubChem Substance ID: 329823820
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: C[C@@H](C(N)=O)[C@H](N)C1=NC2=CC(C(C)(C)C)=CC=C2N1
• InChI: 1S/C15H22N4O/c1-8(13(17)20)12(16)14-18-10-6-5-9(15(2,3)4)7-11(10)19-14/h5-8,12H,16H2,1-4H3,(H2,17,20)(H,18,19)/t8-,12+/m1/s1
• InChI key: APWZIFIAVVFPNT-PELKAZGASA-N

Description

Biochem/physiol Actions

PF-06305591 is a potent and highly selective sodium channel Nav1.8 inhibitor.

PF-06305591 is safe and has acceptable absorption, distribution, metabolism, and elimination (ADME) properties.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable