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Key Documents

PLA0168

Sigma-Aldrich

Rabbit anti-Filamin A Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

ABP-280, ABPX, Actin-binding protein 280, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD, actin binding protein 280, alpha, alpha (actin binding protein 280), alpha filamin, alpha-filamin, endothelial actin-binding protein, filamin A, filamin-1, non-muscle filamin

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human, mouse

technique(s)

immunohistochemistry: 1:500- 1:2,000
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_001447.1

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... FLNA(2316)

Immunogen

The epitope recognized by PLA0168 maps to a region between residue 2597 and 2647 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able act as a link between cell membrane receptors and intracellular signaling proteins. Defects in Filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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