P3886
Poly-L-proline
suitable for ligand binding assays, Mol wt >30,000
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About This Item
Empirical Formula (Hill Notation):
C5H9NO2
CAS Number:
Molecular Weight:
115.13
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
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Product Name
Poly-L-proline, mol wt >30,000
form
powder
Quality Level
mol wt
>30,000
technique(s)
ligand binding assay: suitable
color
white to light yellow
storage temp.
−20°C
SMILES string
OC(=O)C1CCCN1
InChI
1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
InChI key
ONIBWKKTOPOVIA-UHFFFAOYSA-N
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Analysis Note
Molecular weight based on viscosity.
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Helena Bysell et al.
Langmuir : the ACS journal of surfaces and colloids, 25(1), 522-528 (2008-12-09)
The relative importance of electrostatic and nonelectrostatic interactions in peptide-microgel systems was evaluated by micromanipulator-assisted light microscopy, confocal microscopy, and circular dichroism. For this purpose, the interaction of various homopolypeptides with lightly cross-linked polyelectrolyte gel particles ( approximately 70 microm
M Ashtari et al.
Journal of chromatography. A, 1265, 70-87 (2012-10-17)
Poly-proline chains and derivatives have been recently examined as the basis for new chiral stationary phases in high performance liquid chromatography. The selectivity of poly-proline has been measured for peptides with up to ten proline units. In this article, we
Biochemistry. Getting past polyproline pauses.
Allen R Buskirk et al.
Science (New York, N.Y.), 339(6115), 38-39 (2013-01-05)
Michael A Purdy
Journal of virology, 86(18), 10186-10193 (2012-07-20)
The hepatitis E virus (HEV) polyproline region (PPR) is an intrinsically unstructured region (IDR). This relaxed structure allows IDRs, which are implicated in the regulation of transcription and translation, to bind multiple ligands. Originally the nucleotide variability seen in the
Christopher J Woolstenhulme et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(10), E878-E887 (2013-02-23)
Although the ribosome is a very general catalyst, it cannot synthesize all protein sequences equally well. For example, ribosomes stall on the secretion monitor (SecM) leader peptide to regulate expression of a downstream gene. Using a genetic selection in Escherichia
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