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M5308

L-Methionine

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

L-Methionine

Synonym(s):

(S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid

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About This Item

Linear Formula:
CH3SCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
149.21
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-562-9
MDL number:
Beilstein/REAXYS Number:
1722294
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Product Name

L-Methionine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

biological source

non-animal source

Quality Segment

agency

USP/NF, meets EP testing specifications, meets JP testing specifications, meets USP testing specifications

product line

BioXtra

assay

99.0-101.0%

form

powder

quality

meets EP, JP, USP testing specifications

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

284 °C (dec.) (lit.)

solubility

H2O: 25 mg/mL

application(s)

peptide synthesis
pharmaceutical (small molecule)

SMILES string

CSCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

FFEARJCKVFRZRR-BYPYZUCNSA-N

Gene Information

rat ... Ggt1(116568)

Application

L-Methionine has been used as a component of media to culture various cancer cells and to study its effects on the cell cycle. It has also been used as a component of DMEM medium to culture satellite cells from the white muscle of trouts.

Biochem/physiol Actions

Methionine is an essential amino acid which acts a precursor for transmethylation and transsulphuration. In proteins, L-methionine is the biologically active form. The adenosylation of methionine results in the formation of S-adenosyl-L-methionine (SAM), which serves as a methyl donor to various substances. L-Methionine′s metabolic product glutathione is known to regulate immune response and has antiviral action.

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1 of 1

This Item
M9625M84391411504
form

powder

form

powder

form

powder

form

-

assay

99.0-101.0%

assay

≥98% (HPLC)

assay

≥99%

assay

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

product line

BioXtra

product line

-

product line

-

product line

-

impurities

endotoxin, tested

impurities

-

impurities

endotoxin, heavy metals, trace metals, residual solvents, tested

impurities

-

Quality Level

300

Quality Level

200

Quality Level

400

Quality Level

-


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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