G7294

Guanidine hydrochloride solution

8 M, pH 8.5, buffered aqueous solution

• Synonym(s): Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, GuHCl, Guanidine HCl, Guanidinium chloride, Guanidium chloride
• NACRES: NA.25
• UNSPSC Code: 12352209

Properties

• form: buffered aqueous solution
• Quality Segment: 200
• concentration: 8 M
• color: colorless
• pH: 8.5
• application(s): diagnostic assay manufacturing

Description

Application

Guanidine hydrochloride solution has been used:

• as a denaturing agent during the preparation of HEK293T cells and in the resuspension buffer to prevent protein aggregation during the homogenization process in mouse tissue preparation.
• for the extraction of total RNA from plant samples.
• for the digestion of plasma and HDL proteins.
• for the denaturation of proteins during the conformational stability assay of misfolded prion proteins.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Warning
• hcodes: H290,H302 + H332,H315,H319
• pcodes: P234 - P261 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
• Storage Class: 10 - Combustible liquids