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Ferric citrate

Name: Ferric citrate
Brand: SIGMA

BioReagent, suitable for cell culture

Synonym(s):

Iron(III) citrate, Iron(III) citrate hydrate

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About This Item

Empirical Formula (Hill Notation):

C₆H₅FeO₇

CAS Number:

3522-50-7

Molecular Weight:

244.94

NACRES:

NA.75

PubChem Substance ID:

24894843

UNSPSC Code:

12352205

EC Number:

222-536-6

MDL number:

MFCD00013098

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Properties

biological source

synthetic (organic)

Quality Segment

300

product line

BioReagent

technique(s)

cell culture | mammalian: suitable

solubility

hot water: 0.01 g/mL, clear, orange-yellow

shipped in

ambient

storage temp.

room temp

SMILES string

OC12CC(=O)O[Fe](OC(=O)C1)OC2=O

InChI

1S/C6H8O7.Fe/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3

InChI key

NPFOYSMITVOQOS-UHFFFAOYSA-K

Description

Application

Ferric citrate provides a source of iron used in cell culture applications. It provides iron in a less toxic form than free iron salts. Ferric citrate has been used as medium supplement in human osteosarcoma cell (U2OS) culture, human embryonic kidney (HEK293) cells and adult primary cardiomyocytes.

Biochem/physiol Actions

Ferric citrate is used as a component of protein-free medium. It is used as a substitute for transferrin in mouse hybridomas culture. Ferric citrate enhances IgM production. It indirectly stimulates the mitogen-activated protein kinase (MAPK) by favoring high amphiregulin oncoprotein levels in colon cancer. Ferric citrate is effective in binding to phosphate in patients with dialysis-dependent chronic kidney disease.

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This Item	F6129	E6760	EDFS
Sigma-Aldrich F3388 Ferric citrate	Sigma-Aldrich F6129 Iron(III) citrate	Sigma-Aldrich E6760 Ethylenediaminetetraacetic acid ferric sodium salt	Sigma-Aldrich EDFS Ethylenediaminetetraacetic acid iron(III) sodium salt
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| plant: suitable	technique(s) -
biological source synthetic (organic)	biological source -	biological source -	biological source synthetic (organic)
shipped in ambient	shipped in -	shipped in -	shipped in -
solubility hot water: 0.01 g/mL, clear, orange-yellow	solubility -	solubility -	solubility water: 50 mg/mL, clear to slightly hazy, yellow to brown
storage temp. room temp	storage temp. -	storage temp. room temp	storage temp. room temp
Quality Level 300	Quality Level 300	Quality Level 200	Quality Level 300

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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