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3,5-Diiodo-L-thyronine

Name: 3,5-Diiodo-<SC>L</SC>-thyronine
Brand: SIGMA

thyroid hormone analog

Synonym(s):

3,5-Diiodo-4-(4-hydroxyphenoxy)-L-phenylalanine, 3,5-T2, O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₃I₂NO₄

CAS Number:

1041-01-6

Molecular Weight:

525.08

UNSPSC Code:

41116107

NACRES:

NA.26

PubChem Substance ID:

24893248

EC Number:

213-867-7

Beilstein/REAXYS Number:

2707891

MDL number:

MFCD00064987

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Properties

Quality Segment

200

assay

≥99% (HPLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

mp

255 °C

storage temp.

−20°C

SMILES string

N[C@@H](Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1)C(O)=O

InChI

1S/C15H13I2NO4/c16-11-5-8(7-13(18)15(20)21)6-12(17)14(11)22-10-3-1-9(19)2-4-10/h1-6,13,19H,7,18H2,(H,20,21)/t13-/m0/s1

InChI key

ZHSOTLOTTDYIIK-ZDUSSCGKSA-N

Description

Biochem/physiol Actions

3,5-Diiodo-L-thyronine ((T(2)) is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.

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This Item	D0754	T2877	489816
Sigma-Aldrich D0629 3,5-Diiodo-L-thyronine	Sigma-Aldrich D0754 3,5-Diiodo-L-tyrosine dihydrate	Sigma-Aldrich T2877 3,3′,5-Triiodo-L-thyronine	Sigma-Aldrich 489816 L-Tyrosine-(phenyl-3,5-d₂)
description thyroid hormone analog	description crystalline	description ≥95% (HPLC), powder	description 98 atom % D, 99% (CP)
form powder	form crystalline	form powder	form solid
assay ≥99% (HPLC)	assay ≥98.0% (HPLC)	assay ≥95% (HPLC)	assay 99% (CP)
technique(s) ligand binding assay: suitable	technique(s) ligand binding assay: suitable	technique(s) transfection: suitable	technique(s) -
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. -
mp 255 °C	mp 200 °C (dec.) (lit.)	mp 234-238 °C (lit.)	mp >300 °C (dec.) (lit.)
color white to off-white	color white	color -	color -

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hcodes

H412

pcodes

P273 - P501

Hazard Classifications

Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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