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p-Coumaric acid

Name: <I>p</I>-Coumaric acid
Brand: SIGMA

≥98% purity (HPLC), powder

Synonym(s):

trans-4-Hydroxycinnamic acid

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About This Item

Linear Formula:

HOC₆H₄CH=CHCO₂H

CAS Number:

501-98-4

Molecular Weight:

164.16

NACRES:

NA.47

PubChem Substance ID:

24893127

UNSPSC Code:

12171500

MDL number:

MFCD00004399

Beilstein/REAXYS Number:

2207383

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Properties

Product Name

p-Coumaric acid, ≥98.0% (HPLC)

Quality Level

200

assay

≥98.0% (HPLC)

form

powder

technique(s)

titration: suitable

color

white to yellow

mp

214 °C (dec.) (lit.)

solubility

ethanol: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

OC(=O)\C=C\c1ccc(O)cc1

InChI

1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+

InChI key

NGSWKAQJJWESNS-ZZXKWVIFSA-N

Description

Application

p-Coumaric acid has been used as a component of chemiluminescent substrate for protein detection in western blotting.

Biochem/physiol Actions

In western blot, p-coumaric is also used as an enhancer in chemiluminescent substrate.

Hydroxycinnamic acid found in many fruits and vegetables.

Other Notes

Predominantly trans isomer.

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Show Differences

1 of 1

This Item	371335	H1252	722812
Sigma-Aldrich C9008 p-Coumaric acid	Sigma-Aldrich 371335 4′-Hydroxy-4-biphenylcarboxylic acid	Sigma-Aldrich H1252 Homovanillic acid	Sigma-Aldrich 722812 p-Coumaric acid-1,2,3-¹³C₃
technique(s) titration: suitable	technique(s) -	technique(s) titration: suitable	technique(s) mass spectrometry (MS): suitable
color white to yellow	color -	color white to off-white	color -
solubility ethanol: 50 mg/mL	solubility -	solubility ethanol: 50 mg/mL, colorless to light yellow	solubility -
form powder	form powder, crystals or chunks	form powder	form solid
application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology	application(s) diagnostic assay manufacturing hematology histology	application(s) -
assay ≥98.0% (HPLC)	assay 99%	assay >99% (TLC)	assay 99% (CP)

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Enhanced chemiluminescence (ECL) for routine immunoblotting: An inexpensive alternative to commercially available kits.

Mruk DD and Cheng CY

Spermatogenesis, 1, 121-122 (2011)

A cost effective non-commercial ECL-solution for Western blot detections yielding strong signals and low background.

Haan C and Behrmann I

Journal of Immunological Methods, 318, 11-11 (2007)

Inflammation triggers high mobility group box 1 (HMGB1) secretion in adipose tissue, a potential link to obesity.

Gunasekaran MK, et al.

Cytokine, 64, 103-111 (2013)

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Global Trade Item Number

SKU	GTIN
C9008-25G	04061835347315
C9008-10G	04061835347292
C9008-1G	04061835347308
C9008-5G	04061835347322

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