A9451

Aristolochic acid I sodium salt

powder, ≥97%

• Synonym(s): Aristolochic acid sodium salt
• Empirical Formula (Hill Notation): C₁₇H₁₀NNaO₇
• CAS Number: 10190-99-5
• Molecular Weight: 363.25
• NACRES: NA.77
• PubChem Substance ID: 24891454
• UNSPSC Code: 12352202
• EC Number: 233-463-4
• MDL number: MFCD00210760
• Assay: ≥97%
• Form: powder
• Solubility: H₂O: 50 mg/mL

Properties

• Quality Segment: 200
• assay: ≥97%
• form: powder
• solubility: H₂O: 50 mg/mL
• SMILES string: [Na+].COc1cccc2c1cc([N+]([O-])=O)c3c(cc4OCOc4c23)C([O-])=O
• InChI: 1S/C17H11NO7.Na/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13;/h2-6H,7H2,1H3,(H,19,20);/q;+1/p-1
• InChI key: BQVOPWJSBBMGBR-UHFFFAOYSA-M

Description

Biochem/physiol Actions

Component of some Chinese herbal medicines, and responsible for their nephrotoxicity. Prodrug activated by reduction of the nitro group to an amine, which forms cytotoxic DNA adducts.

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 + H311 + H331,H351
• pcodes: P202 - P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges