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A7736

Sigma-Aldrich

Albumin human

recombinant, expressed in Pichia pastoris, lyophilized powder, ≥90% (agarose gel electrophoresis)

Synonym(s):

Albagen, rHSA

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About This Item

Empirical Formula (Hill Notation):
C2936H4624N786O889S41
CAS Number:
Molecular Weight:
66471.53
EC Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.25

biological source

human

recombinant

expressed in Pichia pastoris

Assay

≥90% (agarose gel electrophoresis)

form

lyophilized powder

mol wt

monomer ~67 kDa

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

storage temp.

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Gene Information

human ... ALB(213)

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Application

This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.

Biochem/physiol Actions

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Physical properties

Construct with a single deletion of Asp from the N-terminus to create a hypoallergenic construct. Structural equivalence to native albumin confirmed x-ray crystallography. The Asp deletion eliminates an important antigenic determinant by eliminating the principal copper and nickel binding site of albumin. The first three residues of human albumin are considered non-structural. Also blocked at Cys34 to improve stability, monomer content and homogeneity.

Other Notes

View more information on human serum albumin.

Legal Information

Albagen is a trademark of Albumin Therapeutics, LLC.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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