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08114

Sigma-Aldrich

Magnesium L-pidolate

98.0-102.0% (calc. on dry substance, T)

Synonym(s):

MAG2, Magnesium (S)-2-pyrrolidone-5-carboxylate, Magnesium 5-oxo-L-proline

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About This Item

Empirical Formula (Hill Notation):
C10H12N2MgO6
CAS Number:
Molecular Weight:
280.52
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

98.0-102.0% (calc. on dry substance, T)

optical activity

[α]/D -24±1.5°, c = 0.5 in H2O

pH

5.5-7.5 (25 °C, 50 mg/mL in H2O)

solubility

H2O: 50 mg/mL, clear, colorless

anion traces

chloride (Cl-): ≤500 mg/kg
nitrate (NO3-): ≤50 mg/kg
phosphate (PO43-): ≤50 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

Ag: ≤5 mg/kg
Al: ≤5 mg/kg
As: ≤0.5 mg/kg
Ba: ≤5 mg/kg
Be: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤10 mg/kg
Li: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Ti: ≤5 mg/kg
Zn: ≤5 mg/kg
Zr: ≤5 mg/kg

SMILES string

O=C1CC[C@H](N1)C(=O)O[Mg]OC(=O)[C@@H]2CCC(=O)N2

InChI

1S/2C5H7NO3.Mg/c2*7-4-2-1-3(6-4)5(8)9;/h2*3H,1-2H2,(H,6,7)(H,8,9);/q;;+2/p-2/t2*3-;/m00./s1

InChI key

JQAACYUZYRBHGG-QHTZZOMLSA-L

Application

Magnesium L-pidolate, or MAG2, has been used in a study to inform radiopharmaceuticals for diagnostic imaging of breast cancer. MAG2 has also been used in a study to assess the influence of the bifunctional chelate on the biological behavior of 99mtc-labeled chemotactic peptide conjugates. MAG2 has also been used in a study to learn more about the antimicrobial peptides from the skin secretions of amphibians.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K Verbeke et al.
Nuclear medicine and biology, 27(8), 769-779 (2001-01-11)
Conjugates of For-MLFK and For-NleLFNleYK with S-benzyl mercaptoacetyl dipeptides containing, respectively, zero, one, and two carboxyl functions in their structures were prepared and labeled with (99m)Tc. In vitro binding studies using isolated human granulocytes indicated specific receptor binding of the
Hideki Abe et al.
Endocrinology, 149(3), 1155-1162 (2007-12-15)
Feedback controls of estrogen in LHRH-1 neurons play a pivotal role in reproductive function. However, the mechanism of estrogen action in LHRH-1 neurons is still unclear. In the present study, the effect of estrogens on intracellular calcium ([Ca(2+)](i)) oscillations in
Anti-MUC1 aptamers: radiolabelling with 99mTc and biodistribution in MCF-7 tumour-bearing mice
Da Pieve, C., et al.
Nuclear Medicine and Biology, 36, 702-710 (2009)
Nicholas C Smith et al.
International journal for parasitology, 51(2-3), 95-121 (2020-12-22)
Toxoplasmosis is caused by Toxoplasma gondii, an apicomplexan parasite that is able to infect any nucleated cell in any warm-blooded animal. Toxoplasma gondii infects around 2 billion people and, whilst only a small percentage of infected people will suffer serious
Weixing Tan et al.
Biochemical and biophysical research communications, 460(3), 639-644 (2015-03-31)
Oligodendrocyte precursor cells (OPCs) differentiation failure is one of the leading causes for remyelination defects in the demyelinating lesions of multiple sclerosis (MS). In this study, we explored the roles of insulin-like growth factor-binding proteins 7 (IGFBP-7) on OPCs differentiation

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