92730

Trimethyl phosphite

≥97%

• Synonym(s): TMP, Methyl phosphite, P(OMe)₃, Trimethoxyphosphine
• Linear Formula: (CH₃O)₃P
• CAS Number: 121-45-9
• Molecular Weight: 124.08
• Beilstein: 956570
• MDL number: MFCD00008350
• UNSPSC Code: 12350000
• PubChem Substance ID: 329770160
• NACRES: NA.22

Properties

• vapor density: 4.3 (vs air)
• Quality Level: 200
• vapor pressure: 17 mmHg ( 20 °C)
• Assay: ≥97%
• form: liquid
• refractive index: n20/D 1.408 (lit.); n20/D 1.408
• bp: 111-112 °C (lit.)
• mp: −78 °C (lit.)
• density: 1.052 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: COP(OC)OC
• InChI: 1S/C3H9O3P/c1-4-7(5-2)6-3/h1-3H3
• InChI key: CYTQBVOFDCPGCX-UHFFFAOYSA-N

Description

Application

Trimethyl phosphite is an organophosphorus ester with flame retardant property. It is generally used as a ligand to form coordinate complexes with transition metals.
Some of its other applications include:

• For N-alkylation of amino-9,10-anthraquinones in imidazolium-based ionic liquids without the use of base and highly polar organic solvents.
• To synthesize dimethyl phenylphosphonate by reacting with phenyl radical generated by the thermal decomposition of phenylazotriphenylmethane (PAT).
• To synthesize aryl phosphonates via P-arylation reaction with silyl triflates.

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H302,H315,H317,H319,H335,H341,H351
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH014
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 82.4 °F - closed cup
• Flash Point(C): 28 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves