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Sigma-Aldrich

Lactoperoxidase from bovine milk

lyophilized, powder, ≥150 U/mg

Synonym(s):

Donor:hydrogen peroxide oxidoreductase, Peroxidase

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About This Item

CAS Number:
Enzyme Commission number:
EC Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.22

form

powder

Quality Level

quality

lyophilized

specific activity

≥150 U/mg

mol wt

Mr ~77500

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

InChI

1S/H2O3/c1-3-2/h1-2H

InChI key

JSPLKZUTYZBBKA-UHFFFAOYSA-N

Gene Information

cow ... LPO(280844)

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Biochem/physiol Actions

Lactoperoxidase catalyzes the oxidation of iodide to iodine by hydrogen peroxide. This activity provides a gentle, specific alternative to chloramine T for the radioiodination of proteins and DNA.

Unit Definition

1 U corresponds to the amount of enzyme which oxidizes 1 μmol ABTS (Cat. No. 11557) per minute at pH 6.0 and 25°C

Other Notes

Lactoperoxidase system of bovine milk, review; Structural and functional properties of; Products of lactoperoxidase-catalyzed oxidation of thiocyanate and halides
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Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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P.I Ohlsson et al.
Protides Biol. Fluid Proc. Colloq., 32, 125-125 (1984)
E.L. Thomas
Immunology Series, 27, 31-31 (1985)
B. Reiter
Immunology Series, 27, 123-123 (1985)
Mohanned Naif Alhussien et al.
Scientific reports, 10(1), 11161-11161 (2020-07-09)
Detection of subclinical mastitis (SCM) in its initial stage can save great economic losses, improve milk quality and animal welfare. We have developed a semiquantitative lateral flow assay for the detection of SCM in dairy cows targeting myeloperoxidase (MPO) enzyme
George A Kastis et al.
Experimental biology and medicine (Maywood, N.J.), 238(2), 209-222 (2013-04-12)
Intratracheal administration of lipopolysaccharide (LPS) in animals is a commonly used model of acute lung injury, characterized by increased alveolar-capillary membrane permeability causing protein-rich edema, inflammation, deterioration of lung mechanical function and impaired gas exchange. Technetium-99-m-labeled diethylene-triamine pentaacetatic acid ((99m)Tc-DTPA)

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