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AmberChrom™ 50WX4 Ion Exchange Resin

AmberChrom™ 50WX4 hydrogen form

hydrogen form, 50-100 mesh

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About This Item

Linear Formula:
(C10H12 · C10H10 · C8H8)x
CAS Number:
69011-20-7
MDL number:
MFCD00132725
UNSPSC Code:
12000000
NACRES:
SB.52
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Product Name

AmberChrom™ 50WX4 hydrogen form, hydrogen form, 50-100 mesh

description

cross-linkage 4%

Quality Level

100

form

beads

moisture

64-72%

technique(s)

LPLC: suitable

matrix

styrene-divinylbenzene (gel)

matrix active group

sulfonic acid functional group

particle size

50-100 mesh

capacity

1.1 meq/mL by wetted bed volume

separation technique

cation exchange

SMILES string

C(C)c3c(cccc3)C=C.c2(c(cccc2)C=C)C=C.c1(ccccc1)C=C

InChI

1S/C10H12.C10H10.C8H8/c2*1-3-9-7-5-6-8-10(9)4-2;1-2-8-6-4-3-5-7-8/h3,5-8H,1,4H2,2H3;3-8H,1-2H2;2-7H,1H2

InChI key

NWUYHJFMYQTDRP-UHFFFAOYSA-N

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General description

Dowex 50WX4 hydrogen form is a nonmacroporous gelform bead resin.[1] Dowex 50WX4 hydrogen form can be used as a column packing material which is used in anion exchange chromatography.[2]

Application

Dowex 50WX4 hydrogen form was used:
  • to investigate the effect of particle size on drug loading and release profiles[3]
  • for conversion of D,L-glyceraldehyde 3-phosphate diethyl acetal (barium salt) on treatment with boiling water to free aldehyde D,L-glyceraldehyde 3-phosphate[4]
Strongly acidic cation exchange resin that meets requirements of FDA Food Additive Regulation 21 CFR 173.25

Other Notes

This strongly acidic cation exchange resin has not been specially processed nor cleaned. We suggest that it be subjected to a suitable preliminary elution and wash.

Legal Information

Amberchrom is a trademark of DuPont de Nemours, Inc.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW8096
MKCS8268
MKCN7438
MKCL2502
MKCG8356

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Superacid polymers: Synthesis and analysis of AlCl3-sulfonic acid resin complexes.
Magnotta, V. L., and B. C. Gates.
Journal of Polymer Science Part A: Polymer Chemistry, 15, 1341-1347 (1977)
Maybelle K Go et al.
Biochemistry, 48(24), 5769-5778 (2009-05-12)
Product distributions for the reaction of glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-(13)C]-GA) catalyzed by triosephosphate isomerase (TIM) in D(2)O at pD 7.0 in the presence of phosphite dianion and in its absence were determined by (1)H NMR
Sebastian Reichau et al.
The Journal of biological chemistry, 286(18), 16197-16207 (2011-04-02)
Tuberculosis remains a serious global health threat, with the emergence of multidrug-resistant strains highlighting the urgent need for novel antituberculosis drugs. The enzyme 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAH7PS) catalyzes the first step of the shikimate pathway for the biosynthesis of aromatic
Seong Hoon Jeong et al.
International journal of pharmaceutics, 361(1-2), 26-32 (2008-06-21)
Complexes of ion-exchange resins and dextromethorphan (DM), a model drug, were prepared using different methods including a batch and a column method with different functional groups, ion-exchange capacity, degree of crosslinking, and resin particle size. Drug loading efficiency, release profiles
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Questions

1–3 of 3 Questions  

  1. How do I clean if there are impurities in the resin?

    1 answer

    1. A specific procedure for cleaning this AmberChrom™ 50WX4 hydrogen form is not available. However, general protocols for ion exchange resin care would be applicable. See the image below for backwashing and regeneration instructions. This is an excerpt from the Ion Exchange General Manual.

      To request the full document, please navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Technical Inquiries" under the Products Section with all the required information so that a member of the Technical Service team can reach out to assist further. Thank you.

      Helpful?

  2. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  3. How can I convert a cation exchange resin from the hydrogen form to the sodium form?

    1 answer

    1. To convert a cation exhcange resin from the hydrogen form to the sodium form, use two to four bed volumes of 0.5-2.0% NaCl or NaOH.

      Helpful?

Reviews

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  1. Madison WI
    • Review 1
    • Votes 0
    1 out of 5 stars.

    Helpful?

    1. Response from MilliporeSigma:

      Thank you for your rating. We encourage customers who experience problems with our products to call or email us for additional technical support. Please visit https://www.sigmaaldrich.com/US/en/support/customer-support to submit a Product Technical Inquiry.

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