33347
AOZ
VETRANAL®, analytical standard
Synonym(s):
3-Amino-2-oxazolidinone, NSC 111187, NSC 196570, NSC 38250
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About This Item
Empirical Formula (Hill Notation):
C3H6N2O2
CAS Number:
Molecular Weight:
102.09
Beilstein:
109430
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
63-69 °C
suitability
passes test for identity
application(s)
clinical testing
format
neat
SMILES string
NN1CCOC1=O
InChI
1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2
InChI key
KYCJNIUHWNJNCT-UHFFFAOYSA-N
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General description
AOZ, also known as 3-amino-2-oxazolidinone, is a metabolite of the synthetic nitrofuran veterinary antibiotic ― furazolidone.
Application
The analytical standard can be used as follows:
- Development of an electrochemical impedimetric immunosensor based on immobilization of a monoclonal antibody on a gold electrode, to determine AOZ in six food samples
- Multi-residue analysis of four nitrofuran metabolites residues in 120 fish samples by ultra high-performance liquid chromatography (UHPLC) combined with tandem mass spectrometry
- Detection and measurement of AOZ in tissue samples obtained from four animals by immunochromatography test stripes based on colloidal gold-monoclonal antibody
- LC-MS/MS analysis of nitrofuran and nitroimidazole metabolite residues in honey samples after their extraction by a modified QuEChERS-based method
- Screening of nitrofuran metabolite residues from shrimp muscle samples by an HPLC method combined with diode array detection
Other Notes
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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Product No.
Description
Pricing
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Monoclonal antibody-based ELISA for the quantification of nitrofuran metabolite 3-amino-2-oxazolidinone in tissues using a simplified sample preparation
Diblikova I, et al.
Analytica Chimica Acta, 540, 285-292 (2005)
Quan Wang et al.
Analytical and bioanalytical chemistry, 410(1), 223-233 (2017-11-01)
There is an urgent need for the rapid and simultaneous detection of multiple analytes present in a sample matrix. Here, a multiplex immunochromatographic test (multi-ICT) was developed that successfully allowed for the rapid and simultaneous detection of four major nitrofuran
Pierre Guichard et al.
Food chemistry, 342, 128389-128389 (2020-12-04)
LC-MS/MS method for confirmation of nitrofuran metabolites in meat and aquaculture products, including the nifursol metabolite (DNSH), was developed. The nitrofuran metabolites investigated were as follows: 3-amino-2-oxazolidinone (AOZ), 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), 1-aminohydantoine (AHD), semicarbazide (SEM) and 3,5-dinitrosalicylic acid hydrazide (DNSH). The
A rapid derivatization method for analyzing nitrofuran metabolites in fish using ultra-performance liquid chromatography-tandem mass spectrometry.
Siyang Wu et al.
Food chemistry, 310, 125814-125814 (2019-11-23)
Jinyan Gong et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1146, 122018-122018 (2020-04-26)
This study established a validated analytical method for the first time on the determination of nitrofuran metabolites, including semicarbazide (SEM), 1-aminohydantoin (AHD), 3-amino-2-oxazolidinone (AOZ) and 3-amino-5-morpholinomethyl-2-oxazolinone (AMOZ) in gelatin Chinese medicine. A C18 column with the mobile phase consisting of
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