MAB11041

Anti-Serotonin receptor 1A Antibody, clone 19A9.2

clone 19A9.2, from mouse

• Synonym(s): 5-hydroxytryptamine (serotonin) receptor 1A, 5-hydroxytryptamine receptor 1A, guanine nucleotide-binding regulatory protein-coupled receptor, Serotonin receptor 1A, G protein coupled receptor, 5-HT1a receptor
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 19A9.2, monoclonal
• species reactivity: human, rat
• technique(s): immunohistochemistry: suitable; western blot: suitable
• isotype: IgMκ
• NCBI accession no.: NP_036717
• UniProt accession no.: P19327
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... HTR1A(3350) ; rat ... Htr1A(24473)

Description

General description

Serotonin receptor 1A, also known as 5-hydroxytryptamine receptor 1A, is a member of the G protein-coupled receptor family. Serotonin receptor 1A has been found to be expressed highly in the septum and hippocampus. Serotonin receptor 1A seems to have an inhibitory effect on Ca2+ channels, via N-channels and L-channels. The receptor actuates voltage-sensitive slowing using the N-channels and actuates steady state inhibition using the L-channels.

Immunogen

KLH-conjugated linear peptide corresponding to rat Serotonin receptor 1A.

Application

Anti-Serotonin receptor 1A Antibody, clone 19A9.2 is an antibody against Serotonin receptor 1A for use in WB, IH.

Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Serotonin receptor 1A in normal human brain tissue.

Research Category
Neuroscience

Research Sub Category
Signaling Neuroscience

Quality

Evaluated by Western Blot in rat brain tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Serotonin receptor 1A on 10 µg of rat brain tissue lysate.

Target description

~40 kDa observed. The calculated molecular weight is 46 kDa

Physical form

Format: Purified

Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Rat brain tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable