AB5566
Anti-Capsaicin Receptor Antibody, CT
serum, Chemicon®
Synonym(s):
Vanilloid Receptor 1, VR1
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
guinea pig
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... TRPV1(7442)
Specificity
Recognizes Capsaicin Receptor (Vanilloid Receptor 1, VR1).
Immunogen
A 22 amino acid peptide corresponding to the C-terminus of the rat Capsaicin Receptor protein (Catalog number AG298).
Application
Anti-Capsaicin Receptor Antibody, C-terminus detects level of Capsaicin Receptor & has been published & validated for use in IH.
Immunohistochemistry: 1:1,000. The antibody reacts well with tissue from the rat dorsal root ganglia.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Physical form
Serum. Liquid. Contains less than 0.02% sodium azide.
Analysis Note
Control
Immunogen peptide (catalog number AG298) is available for preadsorbtion control studies.
Immunogen peptide (catalog number AG298) is available for preadsorbtion control studies.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Transient receptor potential vanilloid type 1 channel (TRPV1) immunolocalization in the murine enteric nervous system is affected by the targeted C-terminal epitope of the applied antibody.
Buckinx, R; Van Nassauw, L; Avula, LR; Alpaerts, K; Adriaensen, D; Timmermans, JP
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society null
Sam M Hermes et al.
Journal of chemical neuroanatomy, 72, 1-7 (2015-12-27)
The vagus nerve is dominated by afferent fibers that convey sensory information from the viscera to the brain. Most vagal afferents are unmyelinated, slow-conducting C-fibers, while a smaller portion are myelinated, fast-conducting A-fibers. Vagal afferents terminate in the nucleus tractus
Shuohao Sun et al.
Neuron, 93(4), 840-853 (2017-02-24)
Coding of itch versus pain has been heatedly debated for decades. However, the current coding theories (labeled line, intensity, and selectivity theory) cannot accommodate all experimental observations. Here we identified a subset of spinal interneurons, labeled by gastrin-releasing peptide (Grp)
Shuang-quan Yu et al.
Acta pharmacologica Sinica, 32(6), 845-852 (2011-06-07)
To investigate the effects of selective knockdown of TRPV1 channels in the lower thoracic and upper lumbar segments of spinal cord, dorsal root ganglia (DRG) and mesenteric arteries on rat blood pressure responses to high salt intake. TRPV1 short-hairpin RNA
Chen Ran et al.
Nature neuroscience, 19(9), 1201-1209 (2016-07-28)
The spinal cord is the initial stage that integrates temperature information from peripheral inputs. Here we used molecular genetics and in vivo calcium imaging to investigate the coding of cutaneous temperature in the spinal cord in mice. We found that
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