475915
Anti-Myeloperoxidase Rabbit pAb
liquid, Calbiochem®
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MPO(4353)
General description
Rabbit polyclonal antibody purified by ammonium sulfate precipitation followed by DEAE-Sephacel ion exchange chromatography. Recognizes the myeloperoxidase protein.
Recognizes myeloperoxidase in human neutrophil granules.
This Anti-Myeloperoxidase Rabbit pAb is validated for use in ELISA, Immunoelectrophoresis for the detection of Myeloperoxidase.
Immunogen
Human
purified, human neutrophil myeloperoxidase
Application
ELISA (≥ 1:4000)
Immunoelectrophoresis (see comments)
Immunoelectrophoresis (see comments)
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Standard Handling (A)
Physical form
In PBS.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Generates a single arc by immunoelectrophoresis against human neutrophil granule extract and purified MPO. Variables associated with assay conditions will dictate the proper working dilution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Martina Maritati et al.
Frontiers in microbiology, 15, 1417049-1417049 (2024-06-24)
The accurate distinction between periprosthetic joint infections (PJI) and aseptic failures (AF) is of paramount importance due to differences in treatment. However, this could be challenging by using the current criteria. Various synovial fluid biomarkers are being assessed to improve
Sean E Gill et al.
American journal of respiratory cell and molecular biology, 55(2), 243-251 (2016-03-05)
Although neutrophils play critical roles in innate immunity, in excess these cells cause severe tissue damage. Thus, neutrophil activation must be tightly regulated to prevent indiscriminant damage. Previously, we reported that mice lacking matrix metalloproteinase (MMP) 7 are protected from
Tobias Deuse et al.
Nature, 509(7502), 641-644 (2014-04-22)
Despite the introduction of antiproliferative drug-eluting stents, coronary heart disease remains the leading cause of death in the United States. In-stent restenosis and bypass graft failure are characterized by excessive smooth muscle cell (SMC) proliferation and concomitant myointima formation with
Kashish Manchanda et al.
Arteriosclerosis, thrombosis, and vascular biology, 38(8), 1859-1867 (2018-06-16)
Objective- The leukocyte heme-enzyme MPO (myeloperoxidase) exerts proinflammatory effects on the vascular system primarily linked to its catalytic properties. Recent studies have shown that MPO, depending on its cationic charge, mediates neutrophil recruitment and activation. Here, we further investigated MPO's
Anna Klinke et al.
JCI insight, 3(11) (2018-06-08)
Pulmonary arterial hypertension (PAH) remains a disease with limited therapeutic options and dismal prognosis. Despite its etiologic heterogeneity, the underlying unifying pathophysiology is characterized by increased vascular tone and adverse remodeling of the pulmonary circulation. Myeloperoxidase (MPO), an enzyme abundantly
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