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457250

Methylene Blue

guanylate cyclase inhibitor, solid

Synonym(s):

Methylthioninium chloride, 3,7- bis(Dimethylamino)phenothiazin-5-ium Chloride, 3,7-bis(Dimethylamino)phenothiazin-5-ium Chloride, Methylene blue

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About This Item

Empirical Formula (Hill Notation):
C16H18ClN3S
CAS Number:
Molecular Weight:
319.85
UNSPSC Code:
12171500
NACRES:
NA.77
MDL number:
Form:
solid
Storage condition:
OK to freeze
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Product Name

Methylene Blue, Inhibitor of soluble guanylate cyclase.

Quality Segment

description

Merck USA index - 14, 6060

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

dark green

solubility

water: 4 mg/mL

shipped in

ambient

storage temp.

10-30°C

SMILES string

[s]1c2c(nc3c1cc(cc3)N(C)C)cc[c](c2)=[N+](C)C.[Cl-]

InChI

1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1

InChI key

CXKWCBBOMKCUKX-UHFFFAOYSA-M

General description

Inhibitor of soluble guanylate cyclase. Organic spin-trap agent that forms stable adducts with oxygen free radicals in solution; biological staining agent. Dye content: ≥85%.

Other Notes

Kannan, M.S., and Johnson, D.E. 1995. Life Sci.56, 2229.
Hedrum, A., et al. 1994. Biotechniques17, 118.
Lim, C.S., and Hunt, C.A. 1994. Biotechniques17, 626.
Yezzi, M.J., et al. 1994. J. Immunol.152, 3064.
Mayer, B., et al. 1993. Biochem. Pharmacol.45, 367.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

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This Item
03978Y0001744516705
description

Inhibitor of soluble guanylate cyclase.

description

concentrate according to Ehrlich, concentrated, aqueous solution

description

European Pharmacopoeia (EP) Reference Standard

description

A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells.

form

solid

form

liquid

form

-

form

solid

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

EDQM

manufacturer/tradename

Calbiochem®

storage temp.

10-30°C

storage temp.

room temp

storage temp.

2-8°C

storage temp.

10-30°C

solubility

water: 4 mg/mL

solubility

-

solubility

-

solubility

DMSO: 100 mg/mL, water: 3 mg/mL, ethanol: 25 mg/mL

storage condition

OK to freeze

storage condition

-

storage condition

-

storage condition

protect from light, OK to freeze


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

WGK

WGK 2



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