420323

KT5720

InSolution, ≥95%

• Synonym(s): InSolution KT5720, PKA Inhibitor VII
• Empirical Formula (Hill Notation): C₃₂H₃₁N₃O₅
• CAS Number: 108068-98-0
• Molecular Weight: 537.61
• MDL number: MFCD00132118
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥95% (HPLC)
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• solubility: DMSO: soluble
• shipped in: wet ice
• storage temp.: −20°C
• InChI: 1S/C32H31N3O5/c1-3-4-5-10-15-39-30(37)32(38)16-23-34-21-13-8-6-11-18(21)25-26-20(17-33-29(26)36)24-19-12-7-9-14-22(19)35(28(24)27(25)34)31(32,2)40-23/h6-9,11-14,23,38H,3-5,10,15-17H2,1-2H3,(H,33,36)/t23-,31+,32+/m0/s1
• InChI key: ZHEHVZXPFVXKEY-RUAOOFDTSA-N

Description

Biochem/physiol Actions

Cell permeable: yes

Product competes with ATP.

Reversible: yes

Target K_i: 56 nM against protein kinase A

Packaging

Packaged under inert gas

Warning

Toxicity: Irritant (B)

Physical form

A 2 mM (50 µg/47 µl) solution of KT 5720 (Cat. No. 420320) in DMSO.

Reconstitution

Following the initial thaw, aliquot and freeze (20°C).

Other Notes

Simpson, C.S., and Morris, B.J. 1995. Neurosci.68, 97.
Cabell, L, and Audesirk, G. 1993. Int. J. Dev. Neurosci.11, 357.
Gadbois, D.M., et al. 1992. Proc. Natl. Acad. Sci. USA89, 8626.
Kase, H., et al. 1987. Biochem. Biophys. Res. Commun.142, 436.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 188.6 °F - (refers to pure substance)
• Flash Point(C): 87 °C - (refers to pure substance)